Nrf2 Modulates the Hybrid Epithelial/Mesenchymal Phenotype and Notch Signaling During Collective Cancer Migration
Hybrid epithelial/mesenchymal cells (E/M) are key players in aggressive cancer metastasis.It remains a challenge to understand how these cell states, which are mostly non-existent in healthy tissue, become stable phenotypes participating in collective cancer migration.The transcription factor Nrf2, which is associated with tumor progression and res