NRF2 MODULATES THE HYBRID EPITHELIAL/MESENCHYMAL PHENOTYPE AND NOTCH SIGNALING DURING COLLECTIVE CANCER MIGRATION

Nrf2 Modulates the Hybrid Epithelial/Mesenchymal Phenotype and Notch Signaling During Collective Cancer Migration

Hybrid epithelial/mesenchymal cells (E/M) are key players in aggressive cancer metastasis.It remains a challenge to understand how these cell states, which are mostly non-existent in healthy tissue, become stable phenotypes participating in collective cancer migration.The transcription factor Nrf2, which is associated with tumor progression and res

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Theoretical Study of Irradiation Effects in Close Binaries

The effect of irradiation is studied in a close binary systemassuming that the secondary component is a point source, moving in a circularorbit.The irradiation effects are calculatedon the atmosphere of the primary component in a 3-dimensional Cartesiancoordinate geometry.In treating the reflection effect theoretically, the totalradiation $(S_mathr

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AGROECONOMIC ASSESSMENT OF THE INFLUENCE OF SOWING METHODS AND SOWING RATES OF SAFLORO DYE SEEDS IN THE VOLGOGRAD REGION

Background.Safflower belongs to the category of insurance oilseeds, it is able to grow and form a seed crop for vegetable oils in extremely arid conditions.The production of safflower seeds is associated with extreme conditions, and therefore it is necessary to clarify in the arid climate of the Volgograd region in the zone of light chestnut soils

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